Prof. Dr. Ali EKİZ

Prof. Dr. Ali EKİZ

Gynecology and Perinatology (Risky Pregnancy) Specialist

With over 15 years of professional experience, dozens of national and international research articles, and most importantly, his smiling face, Gynecology and Perinatology Specialist Prof. Dr. Ali EKİZ is with you.

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Fetal DNA Testing

What is fetal DNA testing?

This test, called fetal DNA, free fetal DNA in maternal blood, extracellular DNA test, NIPT, is a test performed by collecting and analyzing DNA fragments spilled from the placenta into the mother’s blood.

What is the fetal DNA test for?

Fetal DNA test is performed to detect common chromosomal abnormalities. The most common is Down syndrome. The screening success of this test for Down syndrome is 99%.

Can other diseases other than Down Syndrome be screened with the fetal DNA test?

With the fetal DNA test, numerical abnormalities of all 23 pairs of chromosomes can be screened. At the same time, chromosomal structural abnormalities, ie chromosomal breakage diseases (microdeletions), can be investigated.

When is the fetal DNA test done?

Fetal DNA testing can be done after the 9th week of pregnancy. It is a test that can be done during the entire pregnancy process. Ideally, it should be done after the 12th week detailed ultrasound.

Who is the fetal DNA test for?

Fetal DNA test is a test that every pregnant woman can have. However, it is especially recommended for the following groups;

• Pregnant women over 35 years old

• Pregnant women with markers detected in ultrasound examination

• Pregnant women with intermediate risk group in screening tests

• Pregnant women with a history of Trisomy 21 and similar chromosomal anomalies in their previous pregnancy

• Twin pregnancies

• Pregnant women with increased risk in screening tests but who do not want to have amniocentesis

What are the advantages of fetal DNA testing?

Since the fetal DNA test is performed by taking blood from the expectant mother, there is no harm to the baby and no risk of miscarriage.

It can scan for Down Syndrome with a high sensitivity of 99.9%.

It can also be screened for many diseases.

In Rh incompatibility, the Rh group of the baby can be determined.

What are the disadvantages of fetal DNA testing and to whom should not be done?

The success of the fetal DNA test in obese expectant mothers decreases and may not yield results.

After the test that fails twice, amniocentesis should be performed.

Expectant mothers who are carriers of a balanced translocation should undergo amniocentesis, not fetal DNA testing.

Fetal DNA test cannot be done in triplets or more pregnancies.

In babies with anomaly in the detailed ultrasound of 11-14, a diagnostic test, namely CVS, should be performed, not a fetal DNA test.

After a high-risk fetal DNA test, no other test should be performed and amniocentesis should be performed.


You can make your appointment with Perinatology (Risky Pregnancy) Specialist Prof. Dr. Ali Ekiz via the WhatsApp button.

Other Perinatology Topics

Contact us to get information about Perinatology (High-Risk Pregnancy)
Contact us to get information about Detailed Ultrasound
Contact us to get information aboutFetal Echocardiography
Contact us to get information about Genetic Screening Tests
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